Tuberculosis IgG (Mycobacterium t.) ELISA

产品名称：Tuberculosis IgG (Mycobacterium t.) ELISA
产    地：Demeditec 
产品货号：DETUB01
产品规格：96 Tests
其它产品：
Tuberculosis IgA(Mycobacterium t.)  Demeditec DETUB02 96 Tests 1804
Tuberculosis IgM(Mycobacterium t.)  Demeditec DETUB03 96 Tests 1804
产品说明：
Special remarks: The DEMEDITEC Mycobacterium tuberculosis IgG antibody ELISA kit has been designed for the detection and the quantitative determination of specific IgG antibodies against Mycobacterium tuberculosis in serum and plasma.
The antigen used for coating the plates are the recombinant antigens 18, 36 and 40 kD.
Mycobacterioses (tuberculosis, leprosy, atypical mycobacterioses, paratuberculosis, and perhaps Crohn’s Disease) are the infectious diseases of men and animals with the largest diffusion on earth. The infectious agents of tuberculosis are acid-resistant rod-like formed bacteria of the family Mycobacteriaceae, genus Mycobacterium. The germ was detected by Robert Koch in 1882. Owing to the very high infectious power of pathogenic mycobacteria, early diagnosis is essential to prevent spreading of the disease. Convergence of various approaches are necessary to control the mycobacterioses, immune reactions and bacterial shedding being variable during the diseases. However, usual diagnostic procedures were up to now unsatisfactory and did not allow to distinguish among different mycobacterial species. The illness is normally transferred by droplets of saliva from infected persons. The target of the infection are mostly the lungs, but also other organs like the brain, intestinal tract, bones, lymph nodes and kidneys can be afflicted. Tuberculosis is not only found in developing countries with 8 million of new infections yearly, but also in industrialized civilizations, as an actual disease with some thousands of cases yearly. Without treatment, the disease leads in 50% of the cases to death within less than two years. Clinical symptoms are fatigue, loss of weight, lack of appetite, light fever, nocturnal sweat and pain in the chest. Especially patients with HIV are threatened by tuberculosis due to their impaired immune system. A vaccination with living attenuated bacteria is possible (BCG = Bacille Calmette Guérin). This is mostly done with newborn or young children. With older patients, before the vaccination there is normally performed the tuberculin test (Pirquet or Mantoux), where a small amount of tuberculin is injected under the skin. In a positive case, there exist antibodies against Mycobacteria, and a vaccination is not necessary. Up to recently, there have not existed any serological methods to detect tuberculosis antibodies in serum. The only available procedure was besides the skin tuberculin test the direct microscopical identification of the dyed bacteria in sputum. Meanwhile specific antigens have been prepared either by purification of natural material or by recombinant methods. This ELISA test kit for the determination of IgG antibodies uses a cocktail of highly pure proteins in order to determine an immune response against the bacteria in human serum. A fresh or chronically active infection can be diagnosed by IgA and IgM tests, which are also available.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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