Endothelin-1 ELISA

产品名称：Endothelin-1 ELISA
产    地：Demeditec 
产品货号：JP27165
产品规格：96 Tests
其它产品：
Endothelin-1 (Big)  Demeditec JP27168 96 Tests 9218
Endothelin-3 Demeditec JP27169 96 Tests 9218
产品说明：
Special remarks:
Can be used for humans but also for bovine, canine, murine, porcine, rabbit, rat investigations, as the amino acid sequence of Endothelin-1 in these animals is the same like in humans.
Cross rectivity to Endothelin-3 is 0,1%, all other Endothelins < 0,1%
Endothelin-1 (ET-1), a peptide of 21 amino acid residues, is the most potent vasoconstrictor substance known.  The discovery by Rubanyi’s group in 1985 of a peptide termed endothelium-derived contracting factor (EDCF) and the isolation, sequencing, cloning and naming endothelin by Yanagisawa of the most potent vasoconstrictor has led to more understanding of many physiological effects.  ET-1 is known to be one of a family of three mammalian vasoactive peptides including endothelin-2 (ET-2) and endothelin-3 (ET-3).  These related peptides differ from ET-1 at the two and six amino acid residue positions, respectively.  Those genes make three pre-propeptides that are cleaved into three big endothelin molecules, each 39 amino acid long.  A number of reviews of function, molecular biology of the endothelin family of peptides and propeptides are available.  ET-1 has been shown to have potent effects on smooth muscle cells, fibroblasts and to be involved in many disease processes, particularly cardiovascular diseases.  It has been shown to be important in congestive heart failure, renal failure and pulmonary hypertension.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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