TSH canine ELISA

产品名称：TSH canine ELISA
产    地：Demeditec 
产品货号：DEV9955
产品规格：96 Tests
产品说明：
Special remarks:
Thyroid stimulating hormone (TSH, thyrotropin) in dogs is similar in function to TSH found in other mammalian species, including humans. It is a glycoprotein produced by the anterior pituitary gland. Through its action on the thyroid gland, it plays a major role in maintaining normal circulating levels of the iodothyronines, T4 and T3. The production and secretion of TSH is controlled by negative feedback from circulating T4 and T3, and by the hypothalamic hormone TRH (thyrotropin releasing hormone). The TSH molecule is composed of two nonidentical subunits, a and b, that are bound together in a noncovalent manner. Within a species, the TSH a subunit is structurally identical to the a subunits of the related glycoprotein hormones (LH, FSH and chorionic gonadotropin). The b subunit of TSH and the b subunits of the related hormones are structurally hormone-specific, and confer upon them their unique biological activities.
Hypothyroidism is considered to be a common endocrine disorder in dogs, whereas hyperthyroidism in this species is nearly unknown. Most cases of canine hypothyroidism are primary in nature, involving impaired production of the thyroid hormones, T4 and T3. In this condition, elevated TSH levels are expected. Secondary or tertiary hypothyroidism, where thyroid hormone production is low as a consequence of hypothalamic or pituitary disease, is believed to account for less than 5% of canine hypothyroidism cases. In the latter conditions, lowered levels of TSH would be expected. Usually, hypothyroidism in dogs is suspected on the basis of clinical history and the presence of lowered levels of thyroid hormones. However, suppressed thyroid hormone levels are nonspecific indicators of the disease, since they are often observed in nonthyroid illnesses. The evaluation of thyroid function and the diagnosis of hypothyroidism in dogs can be greatly improved through the use of the valid assay for the determination of canine TSH.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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