Prolactin canine ELISA

产品名称：Prolactin canine ELISA
产    地：Demeditec 
产品货号：DEV9944
产品规格：96 Tests
产品说明：
Special remarks:
Canine prolactin (cPRL) is a single-chain polypeptide hormone of the canine anterior pituitary with a molecular mass of approx. 22,000. Prolactin from different species exhibits significant variations in the amino acid sequence. Canine prolactin differs from human prolactin at about 60 percent of all residues.
The secretion of cPRL from the pituitary is inhibited by hypothalamic prolactin-inhibitory factor (PIF). Although dopamine was long thought to be this PIF molecule, today it seems that there is a special peptide with prolactin-inhibiting activities. The release of prolactin is certainly stimulated by different peptides, particularly thyrotropin releasing hormone (TRH) and vasocative intestinal peptide (VIP). Estrogens and progesterone also seem to play a role in the secretion of prolactin, and neurogenic factors influence its release. Milking and suckling are immediately followed by an increase in serum cPRL.
The most important role of prolactin is stimulation of mammary gland growth and lactation. During pregnancy, prolactin levels in canine blood increase slightly; during lactation, significantly. Prolactin has a wide variety of other physiological actions. It affects water and electrolyte balance, metabolism and gonadal function; is an important stress hormone; and seems to play a role in the maintenance of the long interestrous interval in the bitch.
In dogs with pituitary-depent hyperadrenocorticism, prolactin levels in blood were higher than in healthy animals. Prolactin determinations can be used in the therapeutic control of hyperprolactinemia. During a pseudo pregnancy, prolactin is increased. Therapy with alkaloids like bromocriptine lowers PRL levels, and lactation and maternal behaviour are decreased.
The secretory capacity of the pituitary can be tested with the TRH stimulation test.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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