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Mycoplasma pneumoniae IgG ELISA

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产品名称: Mycoplasma pneumoniae IgG ELISA
产品型号: DEMYK01
产品展商: 原装进口
产品文档: 无相关文档

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Mycoplasma pneumoniae IgG ELISA


Mycoplasma pneumoniae IgG ELISA  的详细介绍
Mycoplasma pneumoniae IgG ELISA

产品名称:Mycoplasma pneumoniae IgG ELISA
产    地:Demeditec
产品货号:DEMYK01
产品规格:96 Tests
其它产品:
Mycoplasma pneumoniae IgA Demeditec DEMYK02 96 Tests 1628
Mycoplasma pneumoniae IgM Demeditec DEMYK03 96 Tests 1628
产品说明:
Special remarks: The DEMEDITEC Mycoplasma pneumoniae IgG antibody ELISA kit has been designed for the detection and the quantitative determination of specific IgG antibodies against Mycoplasma pneumoniae in serum and plasma. The antigen used for coating the plates is a purified P1 adhesin from the phylum FH.
Mycoplasms belong to the Mollicutes class. Common characteristics of the six eubacterial genera is the lack of a bacterial cell wall, osmotic fragility and small dimensions, which allow a penetration through a 0.45 µm filter. Also the genome with 600 kbp is significantly smaller compared with gram-positive and gram-negative bacteria. Out of this reason they have never been found as freely living organisms. In nature Mollicutes depend on a host cell, respectively, on a host organism like a parasite.Mycoplasma pneumoniae is a human pathogenic bacterium causing tracheobronchitis and primary atypical pneumonia. Associated with the host cell, surface colonization of human respiratory tract epithelial cells takes place. Also secondary diseases like infarction, encephalitis, chronic neuropathy and the Guillain-Barre syndrome can in some cases be connected with a M. pneumoniae infection.In the laboratory, M. pneumoniae can be grown without a host cell in rich medium supplemented with 10-20% horse serum. Besides the cold agglutinin test and complement fixation reaction CF, ELISA is the method of choice, which shows an excellent sensitivity and the possibility to differentiate between the immunogloblin classes.Specific IgA antibodies were developed more regularly and more rapidly than IgM during an acute infection. IgA titres also started to decrease earlier than IgM or the late-peaking IgG response.It could be shown in various studies, that the determination of all the three immunoglobulin classes is necessary, to monitor each step of the clinical course.
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