Leishmania infantum IgG ELISA

产品名称：Leishmania infantum IgG ELISA
产    地：Demeditec 
产品货号：DEIG0310
产品规格：96 Tests
产品说明：
Special remarks:
INTENDED USE
The Demeditec Leishmania ELISA is intended for the qualitative determination of antibodies against Leishmania infantum in human serum or plasma (citrate).
INTRODUCTION
Leishmania are protozoa belonging to the family trypanosomatidae. The parasites exist in two forms:
the promastigotes in the midgut of the vector insect, and the amastigotes within the phagolysosomes of macrophages in their mammalian hosts. In the macrophages they live as round, non-motile amastigotes (3-7 mm in diameter). The macrophages are ingested by the sandfly during blood-meal and the
amastigotes are released into their stomach. Almost immediately the amastigotes transform in to the motile, elongated (10-20µm), flagellate promastigote form, which migrate to the alimentary tract of the fly  and  after  multiplication  move  forward  to  the  salivary  glands  of  the  insect.
Leishmaniases  are  a globally widespread group of parasitic diseases; the “type” is determined by the primary location of the macrophages that are infected. In humans four different forms of Leishmaniasis with a broad range of clinical  manifestations  are  present;  all  can  have  devasting  consequences.  Leishmaniasis  currently affects some 12 million people in  88 countries, all  but 16 of which are  in the developing  world. It is estimated  that  350  million  people  are  exposed  to  the  risk  of  infection  by  the  different  species  of Leishmania parasite; the annual incidence of new cases is about 2 million (1-1.5 million cases of CL, 500,000  cases  of  VL).  Visceral  leishmaniasis  (VL)  is  the most  severe  form  of  the  disease,  which,  if untreated, has a mortality rate of almost 100%. Like many other tropical diseases, the leishmaniases are related to  economic development and man-made environmental changes,  which  increase exposure  to  the  sandfly  vector.  The  geographical  distribution  is  limited  by  the  distribution  of  the  sandfly.
AIDS and other immunosuppressive conditions increase the risk of Leishmania infected people developing  visceral  illness  (VL).  Leishmania/HIV  co-infections  are  considered  to  be  a  real  “emerging  disease”, especially in south-western Europe, where 25-70% of ***** VL cases are related to HIV infec-tion, and 1.5-9.5% of AIDS cases suffer from newly acquired or reactivated VL. Intravenous drug users have been identified as the main population at risk.
上海玉博生物技术有限公司在为生命科学领域提供丰富的产品与信息资源方面处于国内**地位，公司提供的产品涵盖了二十多个国家近五十万种产品，而且产品的数量与信息在不断的增长和更新，公司提供的产品能够使生命科学工作者加快对生物化学，分子生物学，细胞生物学以及蛋白质组学研究的认知，以及分子诊断和临床医学领域的应用。

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