Temsirolimus **

产品名称：Temsirolimus 
产品货号：Affix  AF3031
产品规格：1 mg
Technical Data
Chemical Name 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate] rapamycin
Biological Description Temsirolimus is a recently developed mTOR inhibitor, with improved aqueous solubility and more favorable pharmaceutical properties compared with the parent compound rapamycin (An Ester analog of Rapamycin). Temsirolimus has shown preclinical and early clinical antitumor activity and is currently in phase III clinical development for the treatment of different solid tumors, including breast cancer
Molecular Weight 1030.2 daltons.
Molecular Formula C59H91NO16
Solubility Soluble in chloroform, water, ethanol (200 mg/mL) and DMSO (200 mg/mL) 
Purity >99 %
Storage instructions Up to one week at 4°C or six months at -20°C.
CAS No. 162635-04-3
References Galanis, E., et al. 2005. J. Clin. Oncol. 23:5294-5304.

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