Mexiletine Hydrochloride

产品名称：Mexiletine Hydrochloride
产品货号：Affix  AF3023
产品规格：50 mg
Technical Data
Chemical Name 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride
Biological Description Mexiletine hydrochloride is a use dependent sodium channel blocker of sodium channels in skeletal muscle tissue. In addition, mexiletine can plays an important role in protecting neuronal tissue from oxidative damage. The aryloxy moiety of mexiletine hydrochloride is very important to its function as a sodium channel blocker, as any change to this structure reduces the potency of the compound.
Molecular Weight 215.7 daltons.
Molecular Formula C11H17NO.HCI
Solubility Soluble to 100 mM in Water and to 100 mM in DMSO
Purity >98%
Storage instructions Up to one week at 4°C or six months at -20°C
CAS No. 5370-01-4
References Bellis et al (2006) Evaluation of the pharmacological activity of the major mexiletine metabolites on skeletal muscle sodium currents. Br.J.Pharmacol. 149 300.

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