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Amlodipine Besylate

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产品名称: Amlodipine Besylate
产品型号: Affix AF3010
产品展商: 原装进口
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Amlodipine Besylate


Amlodipine Besylate  的详细介绍
Amlodipine Besylate

产品名称:Amlodipine Besylate
产品货号:Affix  AF3010
产品规格:50 mg
Technical Data
Chemical Name 2-[(2-Aminoethoxy)methyl]-4-(2-chlo rophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarbo xylic acid 3-ethyl 5-methyl ester benzenesulfonate
Biological Description Amlodipine besylate is a L-type (CaV1), voltage-gated Ca2+ channels.Amlodipine besylate is a DHP that acts as L-type, voltage-gated Ca2+ channel blocker and is used in the clinic to treat hypertension. It inhibited Ca2+ -induced contractions in depolarised rat aorta (IC50 1.9 nM) and displays vasoprotective effects in cardiovascular disease.
Molecular Weight 567.1 daltons
Molecular Formula C20H25ClN2O5*C6H6O3S
Solubility Soluble to 10 mM in water and to 100 mM in DMSO
Purity >99 %
Storage instructions Store at RT
CAS No. 111470-99-6 
References Julius, S. et al. (2004) The Lancet 363, 2022.
 

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