Imatinib, Free Base **

产品名称：Imatinib, Free Base
产品货号：LC  I-5577  
产品规格：1 G
This is the free base form of imatinib; please see the other form of this product, Imatinib, Methanesulfonate Salt, Cat. No. I-5508, for further technical information.  The methanesulfonate salt form of imatinib is used for some or all imatinib formulation for use in humans.
Imatinib is the active ingredient in the drug product sold under the trade name Gleevec® and the other trade names listed above under "Related Terms".  This drug has been approved in at least one country for use in patients with gastrointestinal stromal tumors, chronic myelogenous leukemia and a number of other malignancies.  NOTE:  THE IMATINIB, FREE BASE RESEARCH COMPOUND SOLD BY LC LABORATORIES IS NOT GLEEVEC® NOR ANY OTHER DRUG PRODUCT SPECIFIED BY THE TRADE NAMES LISTED ABOVE UNDER "RELATED TERMS", AND IS NOT FOR HUMAN USE.
NOTE:  the trade names listed above under "Related Terms" are for imatinib-containing drug products and may apply variously to formulations of one or another form of imatinib, such as the free base, mesylate salt, or other forms.
This imatinib product is the free base, whose CAS number is given above.  The CAS number of the methanesulfonate salt is 220127-57-1.
Storage:  Store at or below -20 ºC.  Solubility:  Soluble in DMSO at 25 mg/mL with slight warming; soluble in ethanol at 5 mg/mL with slight warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.  Disposal:  A

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