CD38 PE HB7, ASR, **

产品名称：CD38 PE HB7, ASR, 120 tests
产品货号：eBioscience 8012-0388-120
产品规格：120 tests
CD38 PE
Clone: HB7
Analyte Specific Reagent (ASR): Analytical and performance characteristics are not established.
SKU# 8012-0388
Cat. No. Size
8012-0388-025  25 tests 
8012-0388-120  120 tests 
Description: The HB7 monoclonal antibody reacts with the human CD38 molecule, an approximately 45 kDa type II transmembrane protein. CD38 is an ectoenzyme which catalyses NAD into nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR), both of which are secondary messengers. Expression of CD38 is bimodal during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Additionally CD38 is found in a variety of tissues and other hematopoietic cells (e.g. T cells, NK cells and monocytes). The CD34+CD38- population of hematopoietic stems cells is thought to define the most pluripotent cells (e.g. blast colony forming cells). In addition to surface expression, CD38 has recently been found in the nucleus where it may play a role in monitoring calcium levels.

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