Mouse Granzyme B ELISA Ready-SET-Go! **

产品名称：Mouse Granzyme B ELISA Ready-SET-Go! Set 2 plates (includes plates)
产品货号：eBioscience 88-8022-22
产品规格：2 x 96 tests
Mouse Granzyme B ELISA Ready-SET-Go!®
Also known as: GrzB, GzB
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 88-8022
Cat. No. Size
88-8022-22  2 x 96 tests w/plates 
88-8022-86  10 x 96 tests w/plates 
88-8022-88  10 x 96 tests 
Description: One of the major mechanisms of cell-mediated cytotoxicity involves exocytosis of cytoplasmic granules from the effector cell toward the target cell. The granules contain a number of proteins, including the pore-forming protein perforin and a family of serine proteases called granzymes, including Granzyme B. Granzyme B is present mainly in the granules of CD8+ CTL and natural killer (NK) cells and mediates the lethal hit that kills virus infected and tumorigenic cells. Measurement of release of Granzyme B in response to the appropriate target is useful for evaluating cell-mediated cytotoxicity.

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