Anti-Human PARP1 (Cleaved) Alexa Fluor® 488 (HLNC4) **

产品名称：Anti-Human PARP1 (Cleaved) Alexa Fluor® 488 (HLNC4) 100 tests
产品货号：eBioscience 53-6668-42
产品规格：100 tests
Anti-Human PARP1 (Cleaved) Alexa Fluor® 488
Also known as: poly ADP-ribose polymerase
Clone: HLNC4
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 53-6668
Cat. No. Size
53-6668-41  25 tests 
53-6668-42  100 tests 
Description: This HLNC4 monoclonal antibody reacts with human poly (ADP-ribose) polymerase (PARP1). This ubiquitous 116 kDa nuclear enzyme is involved in DNA repair. During apoptosis, active caspases -3, -6 and -7 cleave PARP1 after Asp214, thereby inactivating PARP1 and generating two apoptotic fragments sized 85 kDa and 25 kDa.
The HLNC4 antibody specifically recognizes the 85 kDa PARP1 fragment produced after cleavage and does not recognize the full-length 116 kDa protein.The following peptide was used as the immunogen: NH2-GVDEVAKKKSKKEKDC-COOH.

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