Anti-Human NG2 Alexa Fluor 488 (9.2.27), **

产品名称：Anti-Human NG2 Alexa Fluor 488 (9.2.27), 100 ug
产品货号：eBioscience 53-6504-82
产品规格：100 ug
Anti-Human Neural/Glial Antigen 2 (NG2) Alexa Fluor® 488
Also known as: Chondroitin Sulfate Proteoglycan, MCSP/melanoma chondroitin sulfate proteoglycan
Clone: 9.2.27
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 53-6504
Cat. No. Size
53-6504-80  25 ug 
53-6504-82  100 ug 
Description: This 9.2.27 monoclonal antibody reacts with human neural/glial antigen 2, which is also known as melanoma chondroitin sulfate proteoglycan (MCSP). This antigen is composed of a 250 kDa N-linked glycoprotein and a >450 kDa proteoglycan. NG2 is present on the surface of >90% of malignant melanomas in addition to some non-melanomic tumors. Moreover, NG2 is expressed on glioma cells, as well as on developing and ***** oligodendrocyte precursor cells. Studies have demonstrated the involvement of this protein in tumor cell proliferation, adhesion, migration, and invasion. NG2 also functions as a coreceptor for alpha4beta1 integrin. Finally, expression of NG2 can be used as a prognostic marker for disorders such as acral letiginous melanoma and infantile acute myeloid leukemia.
The 9.2.27 antibody has been reported to suppress melanoma tumor growth.

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