Anti-Human CD100 Alexa Fluor® 488 eBio133-1C6 **

产品名称：Anti-Human CD100 Alexa Fluor® 488 eBio133-1C6 (133-1C6) 100 tests
产品货号：eBioscience 53-1009-42
产品规格：100 tests
Anti-Human CD100 (SEMA4D) Alexa Fluor® 488
Also known as: Semaphorin 4D
Clone: eBio133-1C6 (133-1C6)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 53-1009
Cat. No. Size
53-1009-41  25 tests 
53-1009-42  100 tests 
Description: The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.

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