Anti-Mouse TIGIT Alexa Fluor® 647 (GIGD7) **

产品名称：Anti-Mouse TIGIT Alexa Fluor® 647 (GIGD7) 100 ug
产品货号：eBioscience 51-9501-82
产品规格：100 ug
Anti-Mouse TIGIT Alexa Fluor® 647
Also known as: VSTM3, WUCAM
Clone: GIGD7
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 51-9501
Cat. No. Size
51-9501-80  25 ug 
51-9501-82  100 ug 
Description: The GIGD7 monoclonal antibody reacts with mouse T cell immunoreceptor with Ig and ITIM domains (TIGIT, VSTM3, WUCAM), a 26 kDa protein that is a member of the poliovirus receptor (PVR) family. In mice, the expression of TIGIT has been reported in follicular T helper cells, while in humans, the expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells. TIGIT is not expressed on B cells or naïve CD4+ T cells. TIGIT is upregulated on CD4+ T cells following activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK cells and T cells with antigen presenting cells, fibroblasts and endothelial cells that express PVR and PVR-like proteins.

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