anti-mouse Ly49H Alexa Fluor® 647 3D10 **

产品名称：anti-mouse Ly49H Alexa Fluor® 647 3D10 100 ug
产品货号：eBioscience 51-5886-82
产品规格：100 ug
Anti-Mouse Ly-49H Alexa Fluor® 647 (Discontinued; refer to Cat. No. 17-5886)
Also known as: Ly49H
Clone: 3D10
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: Alternative format APC, Cat. No. 17-5886
SKU# 51-5886
Description: The monoclonal antibody 3D10 recognizes Ly-49H, a member of the C-type lectin Ly-49 multigene family of receptors found on natural killer cells. Ly-49H, like Ly-49D, lacks the characteristic ITIM (immunoreceptor tyrosine-based inhibitory motif) and contains an arginine in the transmembrane domain implying these molecules act as activation receptors. Ly-49H is expressed in a subset of NK cells but not NKT (NK1.1CD3+) cells. Natural killer cells can express several Ly-49 proteins. It has been shown that there is preferential staining of Ly-49H with Ly-49D (cat 12-5783). Expression has been confirmed on C57BL/6 and NWNA but not Balb/c or DBA/2 mice. Other mice strains have not been tested. No crossreactivity to Ly-49A, C, D or G2 has been observed. Addition of monoclonal antibody 3D10 to cell cultures induces lysis of target cells.

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