Alexa Fluor® 647 anti human IREM-1 (CD300LF, CD300f, IREM1) **

产品名称：Alexa Fluor® 647 anti human IREM-1 (CD300LF, CD300f, IREM1) 100 tests
产品货号：eBioscience 51-3008-42
产品规格：100 tests
Anti-Human CD300f (IREM-1) Alexa Fluor® 647
Also known as: IREM1, CLM, MAIR-V, CMRF35-like molecule 1
Clone: UP-D1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 51-3008
Cat. No. Size
51-3008-41  25 tests 
51-3008-42  100 tests 
Description: The monoclonal antibody recognizes human IREM-1 (Immune receptor expressed by myeloid cell 1). IREM-1 is also a member of of the CD300 family specifically referred to as CD300f. IREM-1 is a type I transmembrane protein with a single Ig domain, one predicted N-linked glycosylation site and a long cytoplasmic tail which contains a predicted ITIM domain categorizing it as an inhibitory receptor. Additionally the cytoplasmic domain has been shown to interact with SHP-1 and the p85α subunit of PI3K. Expression is restricted to myeloid cells. In peripheral blood IREM-1 is found on monocytes and granulocytes. In monocyte derived dendritic cells, expression of IREM-1 is downregulated.

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