anti-mouse NKp46 CD335 eFluor 660 (Clone: 29A1.4) **

产品名称：anti-mouse NKp46 CD335 eFluor 660 (Clone: 29A1.4) 100 ug
产品货号：eBioscience 50-3351-82
产品规格：100 ug
Anti-Mouse CD335 (NKp46) eFluor® 660 (Alexa Fluor® 647 Replacement)
Also known as: NCR1, Ly-94
Clone: 29A1.4
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 50-3351
Cat. No. Size
50-3351-80  25 ug 
50-3351-82  100 ug 
Description: The monoclonal antibody 29A1.4 recognizes mouse NKp46, also known as CD335. CD335, a member of the natural cytotoxicity receptor (NCR) family, is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. Expression of CD335 is uniquely found on NK cells (including immature NK cells, defined as DX5- CD3-, and thereby allowing discrimination between NKT cells and NK cells (NKp46+, CD3-). Furthermore, unlike many of the NK markers which also stain NKT cells, staining with 29A1.4 is not strain specific. Staining has been shown on C57Bl/6, SJL, CBA/CA and BALB/C strains. NKp46 has been shown to play a role in NK cell-mediated lysis of several tumor cells and pathogen-infected cell lines.
The 29A1.4 monoclonal antibody has been shown to activate NK cells in vitro. The 29A1.4 monoclonal antibody does not deplete NK cells in vivo.

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