eFluorTM 450 anti-mouse CD106 (VCAM-1) **

产品名称：eFluorTM 450 anti-mouse CD106 (VCAM-1) 100 ug
产品货号：eBioscience 48-1061-82
产品规格：100 ug
Anti-Mouse CD106 (VCAM-1) eFluor® 450
Also known as: VCAM1, vascular cell adhesion molecule-1
Clone: 429
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 48-1061
Cat. No. Size
48-1061-80  25 ug 
48-1061-82  100 ug 
Description: The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.

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