Anti-Human Podoplanin PerCP-eFluor® 710 (NZ-1.3) **

产品名称：Anti-Human Podoplanin PerCP-eFluor® 710 (NZ-1.3) 100 tests
产品货号：eBioscience 46-9381-42
产品规格：100 tests
Anti-Human Podoplanin PerCP-eFluor® 710
Also known as: PDPN
Clone: NZ-1.3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-9381
Cat. No. Size
46-9381-41  25 tests 
46-9381-42  100 tests 
Description: Podoplanin is a 40-kDa type I transmembrane sialomucin-like glycoprotein involved in platelet aggregation and cancer metastasis. This protein is expressed on lymphatic endothelial cells and follicular dendritic cells, as well as on many human cancers, including squamous cell carcinoma, glioblastoma, seminoma, and mesothelioma. Podoplanin expression has been demonstrated to be regulated by the Fos protein of the Activating Protein-1 (AP-1) transcription factor complex. Much of its functionality arises via interaction with its endogenous receptor, C-type lectin-like receptor-2 (CLEC-2).
This antibody has been reported to block the interaction between Podoplanin and CLEC-2.

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