Anti-Mouse V beta 11 TCR PerCP-eFluor® 710 (RR3-15) **

产品名称：Anti-Mouse V beta 11 TCR PerCP-eFluor® 710 (RR3-15) 100 ug
产品货号：eBioscience 46-5827-82
产品规格：100 ug
Anti-Mouse V beta 11 TCR PerCP-eFluor® 710
Clone: RR3-15
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-5827
Cat. No. Size
46-5827-80  25 ug 
46-5827-82  100 ug 
Description: This RR3-15 monoclonal antibody reacts with the mouse T-cell receptor (TCR) V beta 11 chain. Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR3-15 antibody recognizes the V beta 11 chain on T cells from mouse strains with the b haplotype in the Tcrb gene complex, including C57BL/6 and B10, but is absent in mice with the a haplotype, such as C57L, SJL, and SWR. In addition, reports indicate that Vbeta11+ T cells are eliminated in mice bearing the MHC Class II I-E molecule. Finally, V beta 11+CD4+ T cells have been associated with graft-versus-host disease (GVHD) severity.
The RR3-15 antibody has been reported to activate V beta 11+ T cells.

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