Anti-Human TIM3 (clone F38-2E2) PerCP-eFluor® 710, **

产品名称：Anti-Human TIM3 (clone F38-2E2) PerCP-eFluor® 710, 100 tests
产品货号：eBioscience 46-3109-42
产品规格：100 tests
Anti-Human TIM3 PerCP-eFluor® 710
Also known as: T cell immunoglobulin domain, mucin-like domain
Clone: F38-2E2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-3109
Cat. No. Size
46-3109-41  25 tests 
46-3109-42  100 tests 
Description: This F38-2E2 monoclonal antibody reacts with human T cell immunoglobulin and mucin domain-containing molecule (TIM)-3. The cell surface receptor is expressed on activated CD4+ T cell subsets (e.g. Th1, Th17, and Tregs), CD8+ T cells, monocytes, dendritic cells, and mast cells. Due to alternative splicing, TIM3 exists as membrane-bound and soluble forms. Galectin-9 has been identified as the ligand for TIM3. In humans, this receptor negatively regulates CD4+ T cells, influencing the secretion of some Th1- and Th-17-related cytokines. TIM3 has also been implicated in tolerance, autoimmune disease (e.g. multiple sclerosis), and HIV infection.

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