Anti-Human CD166 PerCP-eFluor® 710 (3A6) **

产品名称：Anti-Human CD166 PerCP-eFluor® 710 (3A6) 100 tests
产品货号：eBioscience 46-1668-42
产品规格：100 tests
Anti-Human CD166 (ALCAM) PerCP-eFluor® 710
Also known as: Activated leukocyte cell adhesion molecule
Clone: 3A6
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-1668
Cat. No. Size
46-1668-41  25 tests 
46-1668-42  100 tests 
Description: This 3A6 monoclonal antibody reacts with human CD166, which is also known as activated leukocyte cell adhesion molecule (ALCAM). CD166 is an immunoglobulin superfamily cell adhesion molecule that is broadly expressed on developing and ***** hematopoietic (e.g., activated T and B cells, monocytes, and dendritic cells) and non-hematopoietic (e.g., neural, endothelial, and epithelial) tissues. CD166 has also been detected in melanoma, colorectal carcinoma, as well as cancers of the breast, prostate, and bladder. CD166 mediates cell-cell adhesion by forming low-affinity homophilic interactions (ALCAM-ALCAM) or high-affinity heterophilic interactions with its ligand CD6 (ALCAM-CD6). CD166 plays a role in development, inflammation, and neutrophil migration. Moreover, its expression can be used as a prognostic marker for several cancers and has been reported to be a cancer stem cell marker.
The 3A6 antibody has been reported to induce the internalization of CD166 and its recycling back to the cell surface.

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