Anti-Human CD122 PerCP-eFluor® 710 (9A2-CD122) **

产品名称：Anti-Human CD122 PerCP-eFluor® 710 (9A2-CD122) 100 tests
产品货号：eBioscience 46-1229-42
产品规格：100 tests 
Anti-Human CD122 PerCP-eFluor® 710
Also known as: Interleukin-2 Receptor beta, IL-2Rb, IL-2Rbeta p70, IL-2 receptor beta
Clone: 9A2-CD122
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 46-1229
Cat. No. Size
46-1229-41  25 tests 
46-1229-42  100 tests 
Description: This 9A2-CD122 monoclonal antibody reacts with human CD122, which is also known as interleukin-2 receptor beta (IL-2Rβ). This receptor is expressed on NK cells, activated T cells, some B cells, monocytes, and T cell leukemias. CD122 can also be detected during early NK cell commitment. IL-2Rβ associates with the IL-2Rα (CD25) or IL-15Rα and common γ chain (CD132) to form the high affinity IL-2 and IL-15 receptors, respectively. By itself, this membrane receptor can bind IL-2, but with intermediate affinity. The binding of IL-2 results in internalization of the cytokine, tyrosine phosphorylation of IL-2Rβ, and activation of signaling cascades such as the JAK/STAT pathway.

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