PerCP-Cy5.5 anti-mouse CD26 (DPPIV, THAM) **

产品名称：PerCP-Cy5.5 anti-mouse CD26 (DPPIV, THAM) 100 ug
产品货号：eBioscience 45-0261-82
产品规格：100 ug
Anti-Mouse CD26 PerCP-Cy5.5
Also known as: Dipeptidyl Peptidase IV, DPPIV, DPP4,
Clone: H194-112 (H194-112.12.4.4.5)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 45-0261
Cat. No. Size
45-0261-80  25 ug 
45-0261-82  100 ug 
Description: The monoclonal antibody H194-112 recognizes mouse CD26, a thymocyte-activating molecule (THAM). CD26 is a surface expressed and soluble ectoenzyme (dipeptidyl peptidase IV) that cleaves dipeptides from the amino terminus of proteins. In particular CD26 has been shown to cleave CXCL12, CCL22, neuropeptide Y and glucagon. CD26 is involved in adhesion, apoptosis, disease regulation, and engraftment. Expression is regulated during thymic development at the messenger RNA level. Additionally, CD26 protein is found on thymocytes, a percentage of resting B cells, stimulated B cells, NK cells and a percentage of resting and activated T cells and other epithelial cell types. On human cells more CD26 protein is found on Th2 cells. Functional CD26 is expressed on Sca-1+c-Kit+lin- cells. This expression has been shown to correlate with mobilization of progenitor cells. Inhibition of CD26 activity through a variety of compounds enhances allogenic stem cell homing and engraftment.
This antibody is reported to have activating function.

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