Recombinant Human IL-21

产品名称：Recombinant Human IL-21 4 pack
产品货号：eBioscience 39-8219-65
产品规格：4 Pack
Human IL-21 Single-Use ELISA RSG Standard
Also known as: Interleukin-21, IL21
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 39-8219
Cat. No. Size
39-8219-65  4 pack 
Description: Human Interleukin-21 (IL-21) is a 131-amino acid protein with 57% identity to the mouse gene. It contains a 24-amino acid signal peptide and a 4-helix-bundle cytokine domain homologous to IL-2, IL-4 and IL-15. IL-21 stimulates B cell proliferation in an anti-CD40 dependent manner but inhibits B cell proliferation stimulated by IL-4 plus anti-IgM. IL-21 is induced by IL-6 in activated T cells, a process that is dependent on STAT3 but not on ROR-gamma. IL-21 induces Th17 differentiation and suppresses FOXP3 expression, which requires STAT3 and ROR-gamma.

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