Phycoerythrin-Cy7 (PE-Cy7) anti-mouse CD21/CD35 (CR2/CR1) **

产品名称：Phycoerythrin-Cy7 (PE-Cy7) anti-mouse CD21/CD35 (CR2/CR1) 100 ug
产品货号：eBioscience 25-0211-82
产品规格：100 ug
Anti-Mouse CD21/CD35 PE-Cy7
Also known as: CR2/CR1, C3DR
Clone: eBio8D9 (8D9)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 25-0211
Cat. No. Size
25-0211-80  25 ug 
25-0211-82  100 ug 
Description: The monoclonal antibody eBio8D9 reacts with an eptiope shared by mouse CD21 (CR2) and CD35 (CR1). CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed by mature B cells, but not on thymocytes, peripheral T cells, erythrocytes or platelets. Furthermore, there is some evidence which demonstrates their expression on macrophages. CD21 is a receptor for the complement component C3d and Epstein-Barr virus (EBV). In association with CD19 and CD81, CD21 also participates in B-cell activation through the B cell receptor. Cr2-deficient mice display impaired inflammatory and humoral immune responses in vivo.
The anti-mouse CD21/35 monoclonal antibody clones eBio4E3 and eBio8D9 do not cross-block each other, suggesting that they bind to different epitopes.

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