Phycoerythrin-Cy7 (PE-Cy7) anti-human CD10 (CALLA, NEP, enkephalinase, Neprilys

产品名称：Phycoerythrin-Cy7 (PE-Cy7) anti-human CD10 (CALLA, NEP, enkephalinase, Neprilysin) 100 tests
产品货号：eBioscience 25-0106-42
产品规格：100 tests
Anti-Human CD10 PE-Cy7
Also known as: Common Acute Lymphocytic Leukemia antigen, Neprilysin, CALLA, NEP, Mme
Clone: eBioCB-CALLA (CB-CALLA)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 25-0106
Cat. No. Size
25-0106-41  25 tests 
25-0106-42  100 tests 
Description: The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.

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