2-Color Cocktail - Human: CD4-FITC/CD8a-PE **

产品名称：2-Color Cocktail - Human: CD4-FITC/CD8a-PE 50 tests
产品货号：eBioscience 22-0408-45
产品规格：50 tests
eZFluor™ Anti-Human CD4 FITC and CD8 PE Cocktail
Also known as: CD4 (RPA-T4); CD8a (RPA-T8)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 22-0408
Cat. No. Size
22-0408-45  50 tests 
Description: This product consists of two fluorochrome-conjugated monoclonal antibodies to distinguish human peripheral CD4+ and CD8+ T cells. The RPA-T4 monoclonal antibody (mouse IgG1, κ) reacts with human CD4, a 59 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells (T helper cells) and in low levels on monocytes. CD4 is a receptor for the human immunodeficiency virus (HIV). The RPA-T8 monoclonal antibody (mouse IgG1, κ) reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8αβ) or as a homodimer (CD8αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells.

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