Anti-Human Bcl-6 (clone BCL-UP) APC, **

产品名称：Anti-Human Bcl-6 (clone BCL-UP) APC, 100 tests
产品货号：eBioscience 17-9880-42
产品规格：100 tests
Anti-Human Bcl-6 APC
Also known as: B-cell lymphoma 6
Clone: BCL-UP
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-9880
Cat. No. Size
17-9880-41  25 tests 
17-9880-42  100 tests 
Description: The monoclonal antibody BCL-UP recognizes Bcl-6, also known as B-cell lymphoma 6,which is a member of the POZ family of transcriptional repressors. Bcl-6 is expressed most abundantly in germinal center B cells, as well as in differentiating and activated B cells. This 79 kDa protein is essential for germinal center B cell proliferation and survival. During B cell development, Bcl-6 plays an important role in promoting pre-B cell survival to enable the generation of a diverse B cell repertoire. Moreover, Bcl-6 is expressed constitutively in diffuse large B cell lymphomas (DLBCLs), Burkitt’s lymphoma, and non-Hodgkin’s lymphoma. Reports also suggest expression of Bcl-6 in CD4+ T follicular helper cells and memory T cells. Bcl-6 has been reported to be antagonized by Blimp-1.

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!