Anti-Mouse V beta 11 TCR (clone RR8-1) APC, **

产品名称：Anti-Mouse V beta 11 TCR (clone RR8-1) APC, 100 ug
产品规格：eBioscience 17-5800-82
产品货号：100 ug
Anti-Mouse V alpha 11 TCR APC
Also known as: Valpha11, Va11
Clone: RR8-1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-5800
Cat. No. Size
17-5800-80  25 ug 
17-5800-82  100 ug 
Description: This RR8-1 monoclonal antibody reacts with the mouse T cell receptor (TCR) V alpha 11 chain. Composed of an alpha and beta chain, TCR specificity is typically determined by Va, Ja, Vb, Db, and Jb gene rearrangement. The RR8-1 antibody recognizes the V beta 11 chain on T cells from mouse strains with the b (e.g., C57BL/6, B10) and d (e.g., DBA/1, DBA/2) haplotypes. V alpha 11+ T cells are absent in strains with the a (e.g., BALB/c, C3H) or c (e.g., SJL) haplotypes of the Tcra gene complex. Finally, V alpha 11 is expressed predominantly on CD4+ T cells.
The RR8-1 antibody recognizes the V alpha 11.1 and 11.2 alleles, but not 11.3. This antibody has been reported to stimulate V alpha 11+ T cells.

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