Anti-Mouse CD144 APC (eBioBV13) **

产品名称：Anti-Mouse CD144 APC (eBioBV13) 100 ug
产品规格：eBioscience 17-1441-82
产品货号：100 ug
Anti-Mouse CD144 (VE-Cadherin) APC
Also known as: Cdh5, Cadherin-5, Vascular endothelial cadherin
Clone: eBioBV13 (BV13)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-1441
Cat. No. Size
17-1441-80  25 ug 
17-1441-82  100 ug 
Description: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.

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