Anti-Human CD142 (clone HTF-1) APC, **

产品名称：Anti-Human CD142 (clone HTF-1) APC, 100 tests 
产品规格：eBioscience 17-1429-42
产品货号：100 tests 
Anti-Human CD142 APC
Also known as: Tissue factor
Clone: HTF-1
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 17-1429
Cat. No. Size
17-1429-41  25 tests 
17-1429-42  100 tests 
Description: This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa.
The HTF-1 antibody has been reported to exhibit blocking activity.

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