Functional grade Mouse/human IL-22 (clone IL22JOP), **

产品名称：Functional grade Mouse/human IL-22 (clone IL22JOP), 500 ug
产品货号：eBioscience 16-7222-85
产品规格：500 ug 
Anti-Human/Mouse IL-22 Functional Grade Purified
Also known as: Interleukin-22, IL22
Clone: IL22JOP
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-7222
Cat. No. Size
16-7222-82  100 ug 
16-7222-85  500 ug 
Description: The monoclonal antibody IL22JOP reacts with and inhibits the bioactivity of human and mouse IL-22. IL-22 is a 20 kDa member of the IL-10 cytokine family that is secreted primarily by Th17 cells, NK cells, and other T cells. Compared to IL-6 or TGF beta, IL-23 can induce greater levels of IL-22 in in vitro-differentiated Th17 cells. This observation suggests that IL-22 may be secreted by more fully differentiated Th17 cells in vivo. Recently, it was demonstrated that IL-22 could protect hosts from bacterial infection of the lungs and gut. Moreover, it has been reported that anti-CD3/CD28-induced production of IL-22 by PBMCs was elevated significantly in asthma patients compared to control patients. Flow cytometric analysis also showed that the frequencies of IL-17+IL-22+ CD4 T cells were increased in PBMCs from patients with ankylosing spondylitis and rheumatoid arthritis.

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