anti-mouse CD160 FG Purified eBioCNX46-3 **

产品名称：anti-mouse CD160 FG Purified eBioCNX46-3 (CNX46-3) 500 ug
产品货号：eBioscience 16-1601-85
产品规格：500 ug
Anti-Mouse CD160 Functional Grade Purified
Also known as: BY55
Clone: eBioCNX46-3 (CNX46-3)
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-1601
Cat. No. Size
16-1601-81  50 ug 
16-1601-82  100 ug 
16-1601-85  500 ug 
Description: CD160 is a glycosylphosphatidylinositol (GPI)-anchored Ig-like glycoprotein first identified on human lymphocytes with the monoclonal antibody BY55. In mice, CD160 is expressed on almost all (intestinal intraepithelial lymphocytes) iIELs, NKT cells, most TCRγδ T cells, few NK cells and a minor subset of CD8+ T cells. Murine CD160 has been shown to bind to a wide range of classical and non classical MHC class I molecules and regulate NK cell activation. In vitro, CD3 activation of murine CD8+ T cells increases the expression of CD160 and induces the release of soluble CD160 (sCD160). In human, CD160 mAb cross-linking triggers TNF alpha, IFN gamma and IL-6 cytokine production by peripheral blood NK cells and inhibits tube formation and induces apoptosis of endothelial cells. In mice, cross-linking of CD160 with the CNX46-3 antibody regulates NK cell activation both positively and negatively, depending on the stimulus.

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