anti-mouse CD137 FG Purified 17B5 **

产品名称：anti-mouse CD137 FG Purified 17B5 500 ug
产品货号：eBioscience 16-1371-85
产品规格：500 ug
Anti-Mouse CD137 (4-1BB) Functional Grade Purified
Also known as: Ly-63, TNFRSF9, ILA
Clone: 17B5
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 16-1371
Cat. No. Size
16-1371-81  50 ug 
16-1371-82  100 ug 
16-1371-85  500 ug 
Description: The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays.

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