anti-mouse TIM-1 Purified RMT1-10 **

产品名称：anti-mouse TIM-1 Purified RMT1-10 500 ug
产品货号：eBioscience 14-5862-85
产品规格：500 ug
Anti-Mouse TIM1 Purified (To be Discontinued; refer 0to 14-5861)
Also known as: TIM-1, HAVCR1, T cell immunoglobulin domain, mucin-like domain
Clone: RMT1-10
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: To be disocntinued. Alternative clone is available as 14-5861.
SKU# 14-5862
Cat. No. Size
14-5862-82  100 ug 
14-5862-85  500 ug 
Description: The RMT1-10 monoclonal antibody reacts with mouse TIM-1, a member of newly identified T cell immunoglobulin domain, mucin-like domain (TIM) gene family. RMT1-10 reacts with TIM-1 from C57Bl/6 mouse. RMT1-4, another antibody specific for TIM-1, reacts with the TIM-1 protein from both BALB/c and C57Bl/6 strains. TIM family of proteins are transmembrane proteins expressed by CD4 T cells. Recent studies demonstrate that the TIM family, particularly TIM-1, plays a critical role in immune responses that regulate the development of atopic diseases. Human TIM-1 is a functional receptor for hepatitis A virus (HAV). In humans, certain polymorphic variants of TIM-1 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV). Activation of T cells through TIM-1 by HAV or by its natural ligand may affect T cell differentiation and the development of Th2-driven allergic inflammatory responses.

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