Purified Mouse Nestin (clone rat401),**

产品名称：Purified Mouse Nestin (clone rat401), 100 ug
产品货号：eBioscience 14-5843-82
产品规格：100 ug
Anti-Mouse/Rat Nestin Purified
Also known as: NES, type VI intermediate filament (IF) protein
Clone: Rat-401 (Rat401 (4D4))
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-5843
Cat. No. Size
14-5843-80  25 ug 
14-5843-82  100 ug 
Description: The monoclonal antibody Rat-401 recognizes mouse and rat nestin, a Class VI intermediate filament protein (>170 kDa) primarily expressed in neuroepithelial stem cells. Upon neural differentiation, expression is down-regulated and within the ***** nervous system is limited to progenitor cells in the cortical subventricular zone, the hippocampal dentate gyrus, dorsal root ganglia satellite cells, and a subpopulation of Schwann cells. Nestin expression is also present in other progenitor cell populations such as pancreatic islet, angiogenic endothelial cells, and bone marrow mesenchymal stem cells. Nestin filaments require vimentin and desmin for assembly into heterodimers and polymers. Upon differentiation, Nestin-containing filaments are replaced by cell type specific intermediate filament proteins, such as GFAP.

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