Purified Mouse/human Oct-2 (clone 9A2), **

产品名称：Purified Mouse/human Oct-2 (clone 9A2), 100 ug
产品货号：eBioscience 14-5840-82
产品规格：100 ug
Anti-Human/Mouse OCT2 Purified
Also known as: Oct-2, octamer-binding transcription factor, POU2F2
Clone: 9A2
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-5840
Cat. No. Size
14-5840-80  25 ug 
14-5840-82  100 ug 
Description: This monoclonal 9A2 antibody recognizes human and mouse Oct2, a transcription factor that binds conserved octamer DNA motifs within immunoglobulin promoters. The structure of the Oct2 protein consists of an amino terminal glutamine-rich domain, a central POU homeodomain and a carboxy terminal transactivation domain. Predominantly expressed in the nucleus of B cells, Oct2 has also been found in activated T cells and a subset of myeloid cells. Based on knock-out studies, expression is not required for B cell commitment but is required for maturation. In addition to developmental expression, Oct2 has been associated with neoplasm and maybe a useful tool for characterization of DLBCL and classical Hodgkin’s disease.

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