Affinity Purified anti-mouse GILZ **

产品名称：Affinity Purified anti-mouse GILZ 100 ug
产品货号：eBioscience 14-4033-82
产品规格：100 ug
Anti-Human/Mouse GILZ Purified
Also known as: Glucocorticoid-Induced Leucine Zipper, TSC22D3
Clone: CFMKG15
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-4033
Cat. No. Size
14-4033-80  25 ug 
14-4033-82  100 ug 
Description: GILZ is a leucine-zipper-containing protein that is induced by glucocorticoids. It is expressed in mast cells, monocytes, macrophages, dendritic cells, and T cells. GILZ has been shown to inhibit production of IL-2 as well as TCR-driven upregulation of FasL. GILZ mediates these changes in transcription, at least in part, by inhibiting DNA-binding of the transcription factors AP-1 and NF-κB. GILZ has also been shown to mediate anti-inflammatory signals in macrophages and dendritic cells by interfering with NF-κB-mediated signaling. Although GILZ has been reported to localize to the nucleus, more recent reports as well as testing at eBioscience have observed predominantly cytoplasmic staining.

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