Affinity Purified anti-mouse PDE3B **

产品名称：Affinity Purified anti-mouse PDE3B 100 ug
产品货号：eBioscience 14-1973-82
产品规格：100 ug
Anti-Mouse PDE3B Purified
Also known as: Phosphodiesterase 3b
Clone: SMCP3B
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-1973
Cat. No. Size
14-1973-80  25 ug 
14-1973-82  100 ug 
Description: Cyclic nucleotide phosphodiesterases (PDE) catalyze the hydrolysis of cAMP and cGMP thereby regulating the effects of these second messengers. There are several families of PDE which share common structural organization. The PDE3 family has two members, 3A and 3B that are products of two separate genes. PDE3B (~130 kDa) is expressed predominantly in adipose tissue and lymphocytes, while PDE3A (~120 kDa) is expressed predominantly in platelets and heart tissue.
The monoclonal antibody SMCP3B reacts with mouse PDE3B. The SMCP3B antibody was generated against amino acids 643-1100 in the C-terminus and does not cross-react with mouse PDE3A, as determined by western blot analysis of lysates of mouse heart tissue. The SMCP3B antibody does not cross-react with human PDE3B.

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