Purified mouse/human IL-20R2 (clone 20RNTC), **

产品名称：Purified mouse/human IL-20R2 (clone 20RNTC), 100 ug
产品货号：eBioscience 14-1206-82
产品规格：100 ug
Anti-Human/Mouse IL-20 Receptor 2 (IL-20Rb) Purified
Also known as: Interleukin-20 Receptor
Clone: 20RNTC
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-1206
Cat. No. Size
14-1206-80  25 ug 
14-1206-82  100 ug 
Description: This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.

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