eBioscience 14-0860-85 anti-rat CD86 Purified 24F 500 ug

产品名称： anti-rat CD86 Purified 24F 500 ug
产品货号：eBioscience 14-0860-85
产品规格：100 ug
Anti-Rat CD86 (B7-2) Purified
Also known as: B72
Clone: 24F
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-0860
Cat. No. Size
14-0860-81  50 ug 
14-0860-82  100 ug 
14-0860-85  500 ug 
Description: The 24F monoclonal antibody reacts with rat CD86, an ~90 kDa surface receptor, also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed by germinal center B cells and at low levels on macrophages, dendritic cells and non-lymphoid cells in the thymus. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
 

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