eBioscience 14-0402-86 anti-mouse CD40 Purified HM40-3 1 mg

产品名称：anti-mouse CD40 Purified HM40-3 1 mg
产品货号：eBioscience 14-0402-86
产品规格：1 mg
Anti-Mouse/Rat CD40 Purified
Also known as: TNFRSF5
Clone: HM40-3
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-0402
Cat. No. Size
14-0402-81  50 ug 
14-0402-82  100 ug 
14-0402-85  500 ug 
14-0402-86  1 mg 
Description: The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.
 

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