eBioscience 14-0349-82 anti-human CD34 - reacts with Class III epitope on CD34

产品名称：anti-human CD34 - reacts with Class III epitope on CD34 (Mucosialin) Purified 4H11 100 ug
产品货号：eBioscience 14-0349-82
产品规格：500 ug
Anti-Human CD34 Purified
Also known as: Mucosialin, Class III epitope
Clone: 4H11
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-0349
Cat. No. Size
14-0349-80  25 ug 
14-0349-82  100 ug 
Description: The 4H11 monoclonal antibody reacts with human CD34, also known as mucosialin. CD34 belongs to a protein family which also includes endoglycan and podocalyxin. Members of this family are single pass transmembrane proteins with a heavily glycosylated extracellular and N-terminal mucin domain. CD34 was first identified as an antigen expressed on hematopoietic progenitors, and has since been extensively used as a marker to isolate cells capable of hematopoietic cell engraftment. In spite of this, the function of CD34 remains unresolved. In addition to expression on hematopoietic progenitors, CD34 is expressed on some populations of mesenchymal stem cells, tumor cell lines, and by vascular endothelia in the *****. Epitopes of CD34 have been assigned to three classes (class I, II or III) based on their differential sensitivity to enzymatic cleavage by neuraminidase, chymopapain, or O-glycoprotease. According to this analysis, the 4H11 antibody belongs to class III, indicating that it reacts with a protein epitope.
 

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