eBioscience 14-0292-85 anti-mouse CD29 Purified KMI6 500 ug

产品名称：anti-mouse CD29 Purified KMI6 500 ug
产品货号：eBioscience 14-0292-85
产品规格：500 ug
Anti-Mouse CD29 Purified
Also known as: Integrin β1, platelet GPIIa, ITGB1
Clone: KMI6
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 14-0292
Cat. No. Size
14-0292-81  50 ug 
14-0292-82  100 ug 
14-0292-85  500 ug 
Description: The KMI6 monoclonal antibody reacts with mouse CD29 (integrin β1), a 120-130 kDa member of the β integrin family expressed by leukocytes, endothelial, smooth muscle and epithelial cells. CD29 binds non-covalently with the α integrins CD49a-f, to form the VLA-1 through VLA-6 complexes, respectively, and also with CD51. These αβ integrin heterodimers are capable of mediating a variety of cellular responses including adhesion, trafficking, proliferaton and differentiation. All of the integrins which include CD29 bind to extracellular matrix proteins including collagen, laminin, fibronectin and vitronectin, whereas some CD29-containing integrins also interact with cellular receptors including VCAM-1 and MadCAM-1. The KMI6 antibody has been shown to be an activating antibody for β1 integrins, enhancing lymphocyte binding to fibronectin.

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