eBioscience 13-9974-80 anti-mouse AID Biotin eBio961 25 ug

产品名称：anti-mouse AID Biotin eBio961 25 ug
产品货号：eBioscience 13-9974-80
产品规格：25 ug
Anti-Mouse AID Biotin (To Be Discontinued)
Also known as: Activation-induced cytidine deaminase
Clone: eBio961
RUO: For Research Use Only. Not for use in diagnostic procedures.
Attention: Alternative suggestion is 14-5959. Please note format and application differences.
SKU# 13-9974
Cat. No. Size
13-9974-80  25 ug 
13-9974-82  100 ug 
Description: The eBio961 antibody reacts with mouse activation-induced cytidine deaminase (AID), a member of the cytidine deaminase family, which was cloned from a mouse B-cell lymphoma line induced by combined stimulation with transforming growth factor-beta, interleukin-4, and CD40 ligand. The human AID gene encodes a 198-amino acid protein containing a conserved cytidine deaminase motif. The human AID protein shares 92% amino acid identity with mouse AID. RT-PCR analysis of 15 human tissues detected strong expression of AID mRNA in lymph nodes and tonsils.
Class switch recombination (CSR) is a region-specific DNA recombination reaction that replaces one immunoglobulin (Ig) heavy-chain constant region gene with another. This enables a single variable region gene to be used in conjunction with different downstream heavy-chain constant region genes, each having a unique biologic activity. AID, a putative RNA editing enzyme, is required for this action.
 

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