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eBioscience 13-9039-80 anti-human Toll-like receptor 3 (CD283) Biotin TLR3.7 25

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产品名称: eBioscience 13-9039-80 anti-human Toll-like receptor 3 (CD283) Biotin TLR3.7 25
产品型号: 13-9039-80
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eBioscience 13-9039-80 anti-human Toll-like receptor 3 (CD283) Biotin TLR3.7 25 ug


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eBioscience 13-9039-80 anti-human Toll-like receptor 3 (CD283) Biotin TLR3.7 25 ug

产品名称：anti-human Toll-like receptor 3 (CD283) Biotin TLR3.7 25 ug
产品货号：eBioscience 13-9039-80
产品规格：25 ug
Anti-Human CD283 (TLR3) Biotin
Also known as: TLR-3, toll-like receptor 3
Clone: TLR3.7
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-9039
Cat. No. Size
13-9039-80  25 ug 
Description: The TLR3.7 monoclonal antibody reacts with human Toll-like receptor 3 (TLR3). To date, at least twelve members of the Toll-like receptor family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. In the innate immune response, TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial activity. TLR3 recognizes double-stranded (ds)RNA, induces the activation of NF-κB through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). TLR3.7 suppressed poly(I):poly(C)-mediated IFN-β production by human fibroblasts naturally expressing TLR3 on their surface.
 

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