eBioscience 13-7135-81 anti-mouse IL-13 Biotin eBio1316H 50 ug

产品名称：anti-mouse IL-13 Biotin eBio1316H 50 ug
产品货号：eBioscience 13-7135-81
产品规格：50 ug
Anti-Mouse IL-13 Biotin
Also known as: Interleukin-13, IL13
Clone: eBio1316H
RUO: For Research Use Only. Not for use in diagnostic procedures.
SKU# 13-7135
Cat. No. Size
13-7135-81  50 ug 
13-7135-85  500 ug 
Description: The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6 kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
 

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